Jeffrey
O. Hollinger
Bone Tissue Engineering Center
Carnegie Mellon University
5000 Forbes Avenue
Room 125
Pittsburgh, PA 15213
Phone: 412-268-6498
email:hollinge+@cs.cmu.edu
(1969) B.A., Hofstra
University
(1973) D.D.S.,
University of Maryland
(1978) Residency,
United States Army
(1981) Ph.D.,
University Maryland
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Jeffrey O. Hollinger
Director,
Bone Tissue Engineering Center
Professor
Biomedical and
Health Engineering and
Department of Biological Sciences
Carnegie Mellon University
Research
Interests
My primary research interest focuses on developing treatments to regenerate
bone. Especially important to me are patients with developmental craniofacial
bone problems and geriatric patients who will experience difficulties
with bone healing. Clinical treatments that will benefit these conditions
include cells, gene therapy, signaling molecules, scaffolds, and devices.
Therefore, work in the laboratory has emphasized understanding the basic
principles of these options either alone or in combination, permitting
development as clinical therapies.
Sample
Publications
S.
Winn, J. Bonadio, Y. Hu, and J. O. Hollinger, Cells as Drug
Delivery Platforms, Advanced Drug Delivery Reviews, In Press.
J.O.
Hollinger, S.Winn, and J. Bonadio, Options for Tissue Engineering
to Address Challenges of the Aging Skeleton, Tissue Engineer.
(6)4:341-350, 2000.
S. R. Winn, H. Uludag, and J.O. Hollinger, Carrier
Systems for Bone Morphogenetic Proteins, Clin. Orthop. Rel.
Res., 367: S95-S106. 1999.
S. Winn, G. Randolph, H. Uludag, S. C. Wong, G. Hair,
and J. O. Hollinger, Establishing an Immortalized Human Osteoprecursor
Cell Line: OPC1,
Bone Min. Res., Vol.14(10), 1-13, 1999.
S. Winn, J. Schmitt, D. Buck, Y. Hu, D. Grainger,
and J.O. Hollinger, A Tissue Engineered Bone Biomimetic to Regenerate
Calvarial Critical-Sized Defects in Athymic Rats, Biomed. Mater.
Res., 45, 414-421. 1999.
H.D. Zegzula, D. Buck, J. Brekke, J. Wozney, and
J.O. Hollinger, Bone Formation With Use of rhBMP-2, J. Bone
Joint Surg., 79A(12):1778-1790. 1997
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